General Cell Based Assays
Eurofins Discoverx cAMP Hunter eXpress DRD5 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0094E2CP2M)
The cAMP Hunter DRD5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD5 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type DRD5, a naturally Gs coupled GPCR. Upon activation of DRD5, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-IRS1 (mouse Ser307/human Ser312) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-IRS1 (mouse Ser307/human Ser312) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-CREB (Ser133) Detection Kit, Control Lysate
HTRF Human & Mouse Phospho-CREB (Ser133) Detection Kit, Control Lysate
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-FOXO1 (Ser256) Detection Kit, 10,000 Assay Points
HTRF Human & Mouse Phospho-FOXO1 (Ser256) Detection Kit, 10,000 Assay Points
Indigo Biosciences Human Insulin-Like Growth Factor Receptor 1 (IGF-1R) All-inclusive Cell-Based Luciferase Reporter Assay Kit, 384-well assay plate format
Eliminate weeks of cell culture while achieving superior sensitivity with reproducible results from this all-inclusive cell-based luciferase reporter assay. INDIGO’s Human Insulin-Like Growth Factor Receptor 1 reporter assay allows you to quickly screen test samples to quantify functional activity, either agonist or antagonist, they may exert against Insulin-Like Growth Factor Receptor 1. Kit includes cryopreserved reporter cells engineered to provide constitutive expression of the receptor, optimized media for use during cell thawing and in diluting test samples, reference agonist, Luciferase Detection Reagent, cell culture-ready assay plate, and detailed assay protocol. INDIGO’s unique Cryomite™ process provides exceptional cell viability post-thaw and INDIGO’s strict QA process means consistent results lot to lot (product quality data available upon request).
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-IRS1 (mouse Ser307/human Ser312) Detection Kit, 500 Assay Points
HTRF Human & Mouse Phospho-IRS1 (mouse Ser307/human Ser312) Detection Kit, 500 Assay Points
Cell Signaling Technology Mast Cell ChymaseCMA1 F6S4Q Rabbit mAb 100 ul
Mast Cell ChymaseCMA1 F6S4Q Rabbit mAb 100 ul
Eurofins Discoverx PathHunter eXpress TGFBR1/ACVR2B Dimerization Assay, 10pl Kit. (93-1046E3CP5L)
The PathHunter TGFBR1/ACVR2B Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. GDF-11) induced dimerization of TGFBR1/ACVR2B receptors. This product uses EFC technology. The cell line included overexpresses ACVR2B target protein fused to PK alongside TGFBR1 target protein fused to EA. Upon ligand-induced dimerization of TGFBR1/ACVR2B, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress IL6RA/IL6ST Dimerization Assay, 2pl Kit. (93-1045E3CP5M)
The PathHunter IL6RA/IL6ST Dimerization eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting receptor-receptor interaction. This kit assesses ligand (e.g. IL-6) induced dimerization of IL6RA/IL6ST receptors. This product uses EFC technology. The cell line included overexpresses IL6ST target protein fused to PK alongside IL6RA target protein fused to EA. Upon ligand-induced dimerization of IL6RA/IL6ST, detectable EFC signal is produced. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Cell Biolabs Inc Glutamate Assay Kit (Fluorometric), 200 assays
Excess glutamate levels in the brain can cause cell injury and death, leading to neurological diseases. Cell Biolabs' Glutamate Assay Kit is a quantitative, fluorometric assay that uses glutamate specific enzymes to generate hydrogen peroxide. Glutamate levels as low as 300 nM can be detected in serum, plasma, urine, cell lysates, and cell culture supernatants. Each kit provides sufficient reagents for 200 assays including standards and unknown samples.
ABclonal Technology HRP-conjugated B-Actin Mouse
This gene encodes one of six different actin proteins Actins are highly conserved proteins that are involved in cell motility structure integrity and intercellular signaling The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed Mutations in this gene cause Baraitser-Winter syndrome 1 which is characterized by intellectual disability with a distinctive facial appearance in human patients Numerous pseudogenes of this gene have been identified throughout the human genome
Cell Signaling Technology TUNEL Assay Kit Fluorescence
TUNEL Assay Kit (Fluorescence, 640 nm) 1 Kit;