General Cell Based Assays
Eurofins Discoverx PathHunter eXpress BAI3 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0547E2ACP1L)
The PathHunter BAI3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of BAI3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged BAI3 and EA-tagged β-Arrestin-2. Activation of BAI3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
FUJIFILM Biosciences LumiMAT Pyrogen Detection Kit
MAT NOMO-1 cell line for the detection of endotoxin and non-endotoxin pyrogens
Eurofins Discoverx PathHunter Human GRPR β-Arrestin Cell-Based Assay Kit (HEK 293)
The PathHunter Human GRPR β-Arrestin Stable Cell Line Assay (HEK 293) contains a stable clonal cell line used to measure GRPR (GPCR) activity via recruitment of β-Arrestin2. This is a complete kit that includes the cell vials and all required reagents needed for cell culture and running the assay.
Eurofins Discoverx PathHunter eXpress MRGPRD CHO-K1 β-Arrestin GPCR Assay, 2-Plate Kit. (93-0926E2CP2M)
The PathHunter MRGPRD eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. β-alanine) based activation of MRGPRD GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged MRGPRD and EA-tagged β-Arrestin-2. Activation of MRGPRD stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter IL6RA/6ST Bioassay Kit, 2-Plate. (93-1045Y3-00043)
The PathHunter IL6RA/IL6ST Bioassay kit provides an easy-to-use cell based assay to measure drug potency and detect neutralizing antibodies. This bioassay assesses IL-6-induced dimerization of IL6RA/IL6ST receptors. This product uses EFC technology. The cell line included overexpresses IL6ST target protein fused to PK alongside IL6R target protein fused to EA. Upon ligand-induced dimerization of IL6RA/IL6ST, detectable EFC signal is produced. Bioassay kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, control agonist, detection reagent, and assay plates. For detailed product information, User manual and COA, visit www.discoverx.com/bioassay.
American Research Products Inc Rat eXtracellular superoXide d
Rat eXtracellular superoXide dismutase [Cu-Zn] (Cu/Zn-SOD/SOD3) ELISA kit from CUSABIO Detection Range 15 6 pg/mL-1000 pg/mL Sensitivity 3 9 pg/mL Sample serum plasma cell culture supernates tissue homogenates Method Sandwich
Eurofins Discoverx PathHunter eXpress DRD3 U2OS β-Arrestin GPCR Assay, 2-Plate Kit. (93-0591E3CP0M)
The PathHunter DRD3 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD3 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD3 and EA-tagged β-Arrestin-2. Activation of DRD3 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Revvity Health Sciences Inc HTRF Human Phospho-EGFR (Tyr1068) Detection Kit, 10,000 Assay Points
HTRF Human Phospho-EGFR (Tyr1068) Detection Kit, 10,000 Assay Points
Revvity Health Sciences Inc HTRF Human & Mouse Total CDK4 Detection Kit, 500 Assay Points
HTRF Human & Mouse Total CDK4 Detection Kit, 500 Assay Points
Revvity Health Sciences Inc HTRF Human and Mouse Phospho-p62/SQSTM1 (Ser403) Detection Kit, 10,000 Assay Points
HTRF Human and Mouse Phospho-p62/SQSTM1 (Ser403) Detection Kit, 10,000 Assay Points
Dojindo Molecular Technologies Inc Cellular Senescence Detection Kit (10 plate), detects SA-β-gal with high sensitivity by SPiDER-βGal, applicable to both living and fixed cells, by fluorescence microscopy or flow cytometry.
SPiDER-βGal is a new reagent to detect β-galactosidase specifically which possesses a high cell-permeability and a high retentivity inside cells. This novel reagent can detect β-galactosidase not only in fixed cells but also in living cells, and also can be applied to quantitative analysis by flow cytometry. Senescence-associated beta-galactosidase (SA-β-gal), which is overexpressed in senescent cells, has been widely used as a marker of cellular senescence. Cellular Senescence Detection Kit – SPiDER-βGal is optimized to detect intracellular SA-β-gal. Modern publications with a high number of citations summarize the various features of cellular senescence on the following page (https://www.dojindo.com/senescent-cell-detection-selection-guide/).
Revvity Health Sciences Inc HTRF Human & Mouse Phospho-YAP (Ser127) Detection Kit, 50,000 Assay Points
HTRF Human & Mouse Phospho-YAP (Ser127) Detection Kit, 50,000 Assay Points